I received a notice rom IRS that they have recalculated my 208 return and I owe tax due to the sale of my home? Turbo tax filed my return. Can they help me with this?

TurboTax does not receive any information from the IRS or your state after your return was filed, so no one at TurboTax knows about a letter you received from the IRS or the state.

(what the letters from the IRS mean)

I GOT A LETTER FROM THE IRS   

https://ttlc.intuit.com/questions/3605673-i-got-a-letter-or-notice-from-the-irs

I AM BEING AUDITED

If you purchased Audit Defense:

https://ttlc.intuit.com/questions/2924451-i-bought-max-or-audit-defense-and-now-i-m-being-audited

AUDIT SUPPORT

TurboTax has a special phone number for help with IRS/state tax letters, which will be easier than going through regular Customer Support.   At the page below, click on the blue button that says "Get Help from TurboTax Support".  Then it will ask you what tax year is your letter.  Then it will ask you what the letter concerns. Then it will show you the phone number during posted business hours.

https://support.turbotax.intuit.com/irs-notice/audit-support/

If you purchased Audit Defense for your 2018 tax return, call TaxAudit at 877-829-9695, or report your IRS letter on the TaxAudit.com web site. Do not contact the IRS until you have spoken to TaxAudit. They may contact the IRS on your behalf.

If you did not purchase Audit Defense, you can get help with your IRS letter from TurboTax at the following link.

We can help you with your IRS letter