Do I enter the sale of my house and a purchase of a new house in 2022?

You do not have to report the purchase of your new home anywhere.  You should have a 1098 that represents the mortgage interest on the new home.

The sale of your previous home may not have to be reported either, provided:

• You didn't get a 1099-S.
• You owned the home for at least two years (730 days or 24 full months) during the five years prior to the date of your sale.
• The profit realized from the sale did not exceed $250,000 for a single individual, or $500,000 if married.

If you do have to include the sale on your return:

1. Start at Federal Taxes
2. Select Wages and Income 
3. Click on I'll choose what I work on.
4. Scroll down to Less Common Income.
5. On Sale of Home (gain or loss), click the start or update button.