If you are preparing your home for sale and made major improvements such as remodeled the kitchen or replaced the roof, you can add these to the cost basis to deduct from the profit when you sell the home. You cannot take a deduction prior to the sale of the home for personal residence.
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The cost of improvements to your personal residence, not used as a rental or in a business, is not deductible on a tax return. The cost of the improvements is added to the basis of the home when it is sold.