Is there a difference in the medical expense deduction on the Minnesota return versus the Federal return?

Yes, MN still believes the federal threshold is 10% of your AGI and mirrors this amount. 

Here is the language from the legislature:

For tax year 2017, the federal income tax allows itemized deductions for:

• state and local property and either income or sales taxes
• mortgage and investment interest
• charitable contributions
• medical expenses in excess of 10 percent of income
• casualty and theft losses in excess of 10 percent of income
• job expenses and miscellaneous expenses (most only allowed in excess of 2 percent of income)

Source: www.house.leg.state.mn.us/hrd/issinfo/txdeducs.aspx?src=20

The federal threshold was expected to be 10% until the 7.5% was extended on December 22, 2017. Many of the publications and forms were already drafted for this tax season. At this time, MN has not updated their publications.