Neither. If you purchased a property for 300K and had 30K in sales expenses, for example, when you set up the Cost Basis for your rental property, you could have entered 330K. Then you would begin depreciation from that amount.
However, you could add your original Acquisition Costs now as an Asset, with the original date, and they will be depreciated along with the property.
When reporting the sale, the Sales Proceeds will be allocated to payoff the undepreciated balance of the Acquisition Costs asset, with the rest applied to the undepreciated balance of the Property (and land).
Don't forget to add Sales Expenses to the current Cost Basis to lessen sale gain.
Follow these steps to Report the Sale of Rental Property.