Unemployment made my return drop by almost $4k once I entered it. Is there a calculation to see how much if any refund I am eligible for since $10k is waived

TT Online is already updated to reflect the new unemployment comp deduction.  But you won't qualify for this if your income is too high.  In general, though, any increase in income (including unemployment comp) can lower or eliminate some deductions/credits, so you could be experiencing that as well.

Look at the TT worksheets in your file.

Have you already filed?  I am not sure what you mean by ''is there a calculation''.   You need to report your unemployment income on your tax return.  TurboTax has been updated to include the exclusion.   The calculation is already built into the software, so all you need to do is enter your 1099-G (and all other tax data) to see what refund you are owed.   

TurboTax will exclude up to $10,200 of unemployment income from your tax return if your AGI is under certain thresholds.   But you need to enter all of your W-2s and your 1099-G from unemployment in TurboTax.   If you previously filed without the exclusion, the IRS will refund the difference sometime in May.  If this is the case, when you sign into TurboTax, you will see an updated refund amount and the difference between the amount it shows today and the amount it was when you filed would be the additional amount of refund you should expect from the IRS. 

IRS notice regarding UE compensation