You enter each sale and the sales price and your cost. Turbo Tax calculates the gain or loss.
Enter a 1099 B under
Federal Taxes on left or Personal (Home & Business)
Wages & Income
Then scroll down to Investments and Savings
Then Stocks, Cryptocurrency, Mutual Funds, Bonds, Other (1099-B) - click Start
Then click Add Investments at the bottom
Next screen hit Continue
Then don't enter or pick a bank, at bottom click on Enter a Different Way
Then pick box Stocks, Bonds, Mutual Funds - then Continue
Enter the bank or broker
Answer some general questions and Continue
Then Continue a couple more screens and you finally get to the 1099B entry screen.
You can enter a 1099B manually or try to import it.If you import it be sure to check it over close and make sure the cost basis got imported and is right.How to import your 1099