Can I deduct my Scholars Edge 529 plan contributions from my Massachusetts tax return?

Yes, contributions made to the Scholars Edge 529 plan are deductible.

"Massachusetts allows state residents to deduct annual contributions they make to any Massachusetts 529 Plan from their state income taxes. There is an annual deduction limit of $1,000 for single taxpayers and $2,000 for taxpayers filing married/jointly." - from state tax deduction calculator

As you go through your Massachusetts return, look for a screen titled Education Expenses.  On that page there will be a checkbox labeled Contributed to a College Savings Plan established by Massachusetts.  This is where you will enter your contributions.